1a) of things which on account of some connection with God possess a certain distinction and claim to reverence, as places sacred to God which are not to be profaned
1b) of persons whose services God employs, for example, apostles
2) set apart for God, to be as it were, exclusively his
3) services and offerings
3a) prepared for God with solemn rite, pure, clean
4) in a moral sense, pure sinless upright holy
Neuter of G40; a sacred thing (that is, spot)
KJV Usage: holiest (of all), holy place, sanctuary.